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Abstract: Background: Animal models have demonstrated brain damage upon ethanol intoxication. Tannic acid (TA) demonstrates various medicinal capabilities including neuroprotective potentials. Aim: To investigate the neurobehavioral effects of TA treatments following ethanol-induced prefrontal cortex toxicity. Methodology: Thirty six (36) adult male wistar rats (160g-240g) were assigned into six (6) groups (A to F) of 6 rats each. Group “A” (untreated negative control) received daily doses of distilled water at 6ml/kg/bwt while Group “B” (alcohol control group) received daily doses of 6g/kg/bwt of 40% ethanol only. Group “C, D and E” received daily doses of 6g/kg/bwt of 40% ethanol co-administrated with 200mg/kg/bwt, 100mg/kg/bwt and 50mg/kg/bwt of TA respectively. Group “F” (positive control group) received daily doses of 6g/kg/bwt of 40% ethanol co-administrated with 335mg/kg/bwt of Vitamin-E. All treatments were oral and lasted 14 days. Neurobehavioural investigation was conducted on day 15 via an Open field test (OFT), an Elevated plus maze test (EPM), and a Y-maze test respectively. Following statistical analysis, using one-way ANOVA, p–value≤0.05 was considered as statistically significant. Result: No statistically significant difference was recorded in both time spent in the center and in the periphery during the OFT. No statistically significant difference was recorded in the number of open and closed arm entries in the EPM. No statistically significant difference was recorded in mean percentage alternation between the treatment and control groups in the Y-maze Test. Conclusion: TA did not mitigate or worsen the neurobehavioural effects of ethanol-induced prefrontal cortex toxicity, maintaining the insights on its neuroprotective potentials. 

Keywords: Tannic acid, Neurobehavioral effects, Prefrontal cortex, Wistar rats.

Title: EFFECTS OF TANNIC ACID TREATMENTS ON ETHANOL-INDUCED PREFRONTAL CORTEX TOXICITY: A NEUROBEHAVIOURAL INVESTIGATION

Author: Christian Chiemeka Ozor, Chike Anibeze

International Journal of Recent Research in Life Sciences (IJRRLS)

ISSN 2349-7823

Vol. 11, Issue 4, October 2024 - December 2024

Page No: 34-40

Paper Publications

Website: www.paperpublications.org

Published Date: 24-December-2024

Abstract: This study evaluates the diversity, abundance, and distribution of butterfly species in Gashaka Gumti National Park (GGNP), Taraba State, Nigeria. Butterflies, vital ecological indicators and pollinators, are integral to understanding environmental health and biodiversity conservation. Employing fruit-baited traps and transect walks, butterfly species were sampled over six months, capturing seasonal variations. A total of 100 species comprising 771 individuals were recorded, with Tereas hecabe being the most dominant species (12.84% of total abundance). The Shannon-Weiner Diversity Index (H’) for the park was calculated at 3.797, reflecting high species richness but uneven distribution. Rare species represented 35% of the species pool, underscoring the park's ecological complexity and the importance of habitat heterogeneity. The findings highlight GGNP's role as a biodiversity hotspot and stress the need for targeted conservation strategies to maintain its ecological integrity.

Keywords: Butterfly, Diversity, Abundance, Distribution, Gashaka-Gumti.

Title: THE DIVERSITY, ABUNDANCE AND DISTRIBUTION OF BUTTERFLY’S SPECIES IN GASHAKA GUMTI NATIONAL PARK, TARABA STATE, NIGERIA

Author: David Musa Garkida, Delphine Leila David, Hussaina John Danburam

International Journal of Recent Research in Life Sciences (IJRRLS)

ISSN 2349-7823

Vol. 11, Issue 4, October 2024 - December 2024

Page No: 24-33

Paper Publications

Website: www.paperpublications.org

Published Date: 5-December-2024

Abstract: Vasoplegia is a challenging condition to manage, particularly in intensive care unit (ICU) patients. It is a clinical condition that requires close monitoring and requiring continuous vasopressor support. This is a review highlighting the definition, etiology, and basic management protocol for vasoplegia occurring as a consequence of sepsis.

Keywords: Vasoplegia, Sepsis, septic shock, ICU.

Title: Sepsis-induced vasoplegia; a short review

Author: Osama Mohamed Abbas, Alaweya Ali Ofash, Osama Sharafeldin Abbadi

International Journal of Recent Research in Life Sciences (IJRRLS)

ISSN 2349-7823

Vol. 11, Issue 4, October 2024 - December 2024

Page No: 19-23

Paper Publications

Website: www.paperpublications.org

Published Date: 02-November-2024

Abstract: Traditionally fermented foods play an essential role in the diets of many cultures, often offering health benefits beyond basic nutrition. Gari and Palm wine, two staples in West African cuisine, are rich in lactic acid bacteria (LAB), which are known to contribute to both fermentation processes and potential health benefits. This study focuses on the isolation and characterization of LAB from these fermented products to evaluate their probiotic potential. LAB cultures were grown on MRS agar under both aerobic and anaerobic conditions, with growth observed at 24 and 48 hours, in line with similar studies (Arjun et al., 2012; Amoa-Awa et al., 2007; Nwachukwu et al., 2016). Some variations in incubation times across studies were noted, possibly due to differences in sample preparation and LAB strains used (Ramdass et al., 2014; Olaoluwa et al., 2013). The isolated LAB, identified as Gram-positive, catalase- and oxidase-negative cocci and bacilli, were consistent with previously documented LAB characteristics (Arjun et al., 2012; Amoa-Awa et al., 2007; Nwachukwu et al., 2016). In addition, these LAB showed antimicrobial activity against pathogens such as Staphylococcus aureus and Escherichia coli, supporting findings from prior research (Guo et al., 2009; Dunne et al., 2001). The LAB's survival in acidic environments was confirmed, as they remained viable in diluted hydrochloric acid. These findings emphasize LAB’s role in traditional fermentation and their potential health benefits, underscoring the need for further research into the probiotic properties of LAB in Gari and Palm wine. It is recommended to encourage public education on the probiotic benefits of LAB in traditionally fermented foods and to enhance support for large-scale LAB production for health applications.

Keywords: lactic acid bacteria, probiotic potential, Gari, Palm wine, antimicrobial properties, fermentation.

Title: Characterization and Probiotic Potential of Lactic Acid Bacilli Isolated from Gari and Palm Wine in Ekpoma, Nigeria

Author: Bamidele Adeoba, Ifueko Osaigbovo

International Journal of Recent Research in Life Sciences (IJRRLS)

ISSN 2349-7823

Vol. 11, Issue 4, October 2024 - December 2024

Page No: 1-18

Paper Publications

Website: www.paperpublications.org

Published Date: 29-October-2024