Indexing

Abstract: Contraception is a means or method to prevent pregnancy. Contraceptives are the devices, agents, drugs, etc used in prevention of pregnancy. Basic methods of contraception are: (i) modern methods, and (ii) traditional / herbal methods. Modern method involves the use of vaginal ring, cervical caps, hormonal implants, patch, injections, diaphragm, male/female condoms, spermicides, pills, vasectomy, male/female sterilization, intrauterine device (IUD), intrauterine system (IUS), etc. Traditional/herbal methods involve the use of medicinal and antifertility plants, herbal remedies and recipes, natural family planning methods and other inexplicable traditional forms. Despite these methods, contraceptive prevalence in Nigeria is low. The necessity of producing and developing herbal contraceptives is long overdue in Nigeria due to the adverse effects, cost, inaccessibility, unavailability and undesirability of the modern methods especially to rural dwellers in Nigeria. This paper therefore reviews the necessity of producing and developing herbal contraceptives from the abundance of medicinal plants with antifertility potentials, indigenous knowledge and prescriptions of traditional medicine practitioners (TMPs) in Nigeria.

Keywords: Contraception, family planning, herbal contraceptives, medicinal plants, antifertility.

Title: Production and Development of Herbal Contraceptives in Nigeria – A Necessity

Author: Igwillo U.C., Nwokeke C.C., Nwachukwu V.C., Inchikida B.M., Kure T.K., Danjuma N., Onwubiko J.I, Chukwu U.N.

ISSN 2349-7823

International Journal of Recent Research in Life Sciences (IJRRLS)

Paper Publications

Abstract: The emerging COVID-19 has reached a pandemic level shortly fter the first few detected cases in Wuhan, China. The knowledge of the genetic assembly, mode of replication, transmission, and pathogenesis are cornerstones in the combat against this pandemic. In this short review authors highlighted the main up-to-date information on the abovementioned aspects of the virus, in addition to the major symptoms, and also a highlight of an adapted clinical management held in Sudan, Africa.

Keywords: COVID19, Genome, Viral RNA, Pathogenesis.

Title: COVID-19 Genome and Pathogenesis; A Short Review

Author: Elmuaiz Gasmalbari, Samuel Tekle, Osama Abbadi

ISSN 2349-7823

International Journal of Recent Research in Life Sciences (IJRRLS)

Paper Publications

Abstract: This paper provides valid reasons necessitating the integration of modern and traditional health practices and systems in Nigeria in view of the growing national and global demand for herbal products. Integration of modern and traditional health systems in Nigeria is important in order to harness the enormous benefits inherent in an integrated healthcare system such as: more health manpower, wider health coverage, better utilization of the vast biodiversity of the country and better health status of the people among others. Inherent challenges militating against this integration include; absence of standardization, secrecy associated with the practice, lack of respect and outright denial of the contributions of traditional medicine by western trained doctors and policy makers, informal methods of training the practitioners, lack of documentation, unhygienic manner of handling the products and inadequate government support. Despite these challenges, the way forward includes: official training of practitioners of traditional medicine, standardization of the practice, adequate government support, establishment of a legal framework and regulatory council, independent development of the practice among others.

Keywords: Integration, Modern medicine, Traditional Health Practices, Healthcare, Traditional Medicine.

Title: Integrating Modern and Traditional Health Practices in Nigeria: Challenges and the Way Forward

Author: Nwokeke, C.C., Oyefara, J. L., Adejoh S.O., Igwillo U.C.

ISSN 2349-7823

International Journal of Recent Research in Life Sciences (IJRRLS)

Paper Publications

Abstract: COVID19 had hit the world population and health systems very hard. The current pandemic caused by this virus exposed many weak links in the health management both locally and globally. The effort on combating the disease caused by SARS-CoV-2 should not be limited to finding a cure or a vaccine; supporting managements are also beneficial in reducing the symptoms, boosting immunity, and accelerating the recovery process. In this review the authors spotted the light on some important traditional regimens, minerals, and vitamins that have eminent effects on the management of COVID19.

Keywords: Traditional Medicine, COVID19, Zinc, Iron, Vitamins.

Title: The use of Traditional Medicines, Vitamins, and minerals against COVID-19; a Review

Author: Elmuaiz Gasmalbari, Abdelsamie Elobeid, Osama Abbadi

ISSN 2349-7823

International Journal of Recent Research in Life Sciences (IJRRLS)

Paper Publications

Abstract: This current study aimed to evaluate the hypoglycemic, hypolipidemic, hematological, thermogenic, biomedical, and toxic effects in Albino Rats caused by Acacia nilotica ethanol extract. Acacia nilotcia pods were harvested in Sudan. The animals used in the study were 24 albino Rat males (90-125g). 10 grams of each powdered plant sample were refluxed with 100 ml of 80% of ethanol four 4 hours. The cooled solution was filtered and enough 80% ethanol was passed through the volume of the filtrate to 100 ml. This prepared extract (PE) was used for the various tests. Rats plasmas were tested for Lipid profile, whole blood count, renal functions, and liver functions. Histological sections were taken from the liver and kidneys of the Rats. Result were expressed as mean+_SEM . The data were subjected to one –way analysis of variance (ANOVA). Acacia nilotica administration significantly raised the levels of Proteins, Albumin, ALT, Hemoglobin, RBCs, PCV, and MCV. Acacia also significantly lowered the levels of Blood sugar (RBs), WBCs, Platelets, and caused a marked loss of body weight in albino rats. The changes recorded in Triacylglycerols, Cholesterol, AST, ALP, Urea, or Bilirubin, were statistically insignificant. Administration of Acaia extract to rats can improve their blood profile and protein content, reduce their weights, but also increase their bleeding tendency.

Keywords: Acacia nilotica, Ethanol extract, Albino Rats, Blood levels.

Title: Biochemical, Haematological, and Histopathological Changes caused by Acacia Nilotica on Albino Rats

Author: ELmuaiz Gasmalbari, Hatel ELkmali, Osama Abbadi

ISSN 2349-7823

International Journal of Recent Research in Life Sciences (IJRRLS)

Paper Publications

Abstract: Many of the pharmacological purpose currently available to physicians have history of use as herbal remedies. Many important drug chemicals are derived from plants. This study aimed to screen Moringa oleifera, Acacia nilotica, and Ambrosia maritima contents of some important phytochemicals. Materials and methods: 10 g of each powdered plant sample was refluxed with 100 ml of 80% of ethanol four 4 hours. This prepared extract (PE) was used for the various tests. Phytochemical screening for the active constituents (Triterpenes; Alkaloids; Flavonoids; Tannins; Saponins; and Glycosides) was carried out using the standard methods described in literature with some explained modifications. Results: Acacia represented high amount of Tannins and Sterols. Moringa showed high levels of Flavonoids, Coumarins, and Tannins, few Alkaloids and Saponins, but no Glycosides were detected. Ambrosia maritima expressed copious amounts of Triterpenes and Tannins, but no Sterols were seen. None of the plants shown to contain Cyanogenes. Conclusion: Acacia showed to have the most versatile chemical contents, and moringa showed rich content of Tannins and Flavonoids, while Ambrosia was rich in Triterpenes. The three plants models were in lack of Cyanogenes and only trace amounts of glycosides were observed in Acacia extract. 

Keywords: Acacia, Moringa oleifera, Ambrosia, Phytochemistry.

Title: Comparative phytochemical screening of three medicinal plants: Acacia nilotica; Ambrosia maritima; and Moringa oleifera

Author: ELmuaiz Gasmalbari, Hatil El Kamali, Osama Abbadi, Yassin Babiker Al Hussein

ISSN 2349-7823

International Journal of Recent Research in Life Sciences (IJRRLS)

Paper Publications