Abstract: The medicinal plants as well as the herbs are an important aspect of traditional Chinese medicine and even an enriched source of various chemicals. Among the medicinal herbs, Angelica sinensis, also known as Dong Quai is the most popular used as Chinese medicine. The main compounds found in the acetone extract of Angelica sinensis(AS-AC) are ferulic acid, butylidenephthalide, ligustilide, brefeldin A, angelicide , B-sitosterol, butyl phthalide, calcium channel-blocking compounds (which relax visceral organ muscle) ,carvacrol, coumarins (at least six coumarin derivatives(coumarin content in Dong Quai does not promote phototoxic, carcinogenic or mutagenic effects, but exerts antispasmodic and vasodilatory effects)) including: angelol, angelicone ; essential oils, consisting mainly of Ligustilide , N-butylidenphthalide; ferulic acid, flavonoids, fixed oil ,furanocoumarins ,nicotinic acid ,phytosterols ,polysaccharides ,stigmasterol ,vitamins E, A and B12. This traditional Chinese herbal medicine has various pharmacological and toxicological effects i.e. Cardiovascular effects, Neurological effects, Musculoskeletal effects, Immunological effects/Amineoplastic activity/Antimicrobial activity, Anti-Inflammatory activity, Darmatological effects, Carcinogenicity, Estrogenic effects, Gastrointestinal effects. The aims of this review are to summarize the history and an account of the adverse effects and potential interactions of Dong Quai, and a discussion about therapeutic effects of this herb.
Keywords: Angelica Sinensis, Chinese medicine, Dong Quai, medicinal plant, Pharmacological and biochemical action, Toxicological effects.
Title: Pharmacological and Biochemical Action of Angelica Sinensis (Dong Quai): Natural Product with Therapeutic Potential
Author: Debanjali Bain
ISSN 2349-7823
International Journal of Recent Research in Life Sciences (IJRRLS)
Paper Publications