Abstract: Lacto-vegetarians, lacto-ovo-vegetarians and pesco-vegetarians are put together as vegetarians and people who consume animal products such as meat, poultry, fish, seafood at least once a week are considered as non-vegetarians. The diet is the key factor for tolerance to glucose, urea, salt retention and many enzymes. Na+K+-ATPase, an enzyme present on the surface of RBC membrane, Na+ and K+ are seen to alter with levels of urea and creatitnine, with an altered glucose level and blood pressure. Hence, this study was undertaken to analyse the above hypothesis. The objective of this cross-sectional study was to estimate the levels of serum Na+, K+ in association with erythrocyte membrane Na+-K+ATPase and the status of serum glucose, urea and creatinine in healthy vegetarians and non-vegetarians and a co-relation was done with the diet that individual has. 50 vegetarians and 50 non-vegetarians within the age group 30-40 years were selected with the help of a questionnaire and the analysis of Na+-K+ATPase in erythrocytes and Na+, K+, urea, creatinine and glucose in serum was done in these individuals. ATPase activity was measured by the method of Raccah et al. while serum glucose was estimated by Glucose Oxidase-PerOxidase’s method, urea by DiAcetyl Monoxime’s (DAM) method and creatinine by alkaline creatinine picrate. The Na+ and K+ were measured flame photometrically. Mean and standard deviation of all the serum and erythrocytic parameters were computed and compared using a paired ‘t’ test. The p value was calculated for the comparison among the two groups, i.e., non-vegetarians and vegetarians. The results obtained showed an decrease in the activity of Na+-K+ATPase with an increased Na+, glucose and urea, which was observed to be higher in non-vegetarians when compared to vegetarians. The K+ and creatinine levels did not show any change when compared with the fooding habit of these individuals. Vegetarianism is advantageous as depicted by the lower levels of glucose, urea, Na+, K+ and higher activity of Na+-K+ATPase was observed in this study when compared to the non-vegetarians who had a comparatively higher level of these values and lower activity of Na+-K+ATPase. It strengthens the notion of vegetarianism being preferred to non-vegetarianism with the other studies done on similar fooding habit.
Keywords: Vegetarians, Non-vegetarians, glucose, urea, Na+-K+ATPase.
Title: Variation of Major Cations and Na
+K
+ATPase in Erythrocytes and Its Relation Between the Serum Level of These Cations Along with Glucose, Urea and Creatinine in Vegetarians and Non-Vegetarians - A Cross Sectional Study
Author: Mohit Adhikary, Smita S. Sonoli
ISSN 2349-7823
International Journal of Recent Research in Life Sciences (IJRRLS)
Paper Publications